Showing 4 ideas for tag "BigData"

The Human Placenta Project

Basic Research Premeeting Discussion Summary - L Myatt & Y Sadovsky

Key Achievements/Breakthroughs

• Development of trophoblast and decidual organoids

• Induced pluripotent stem cells

• Introduction of single cell and spatial technology to probe placental biology

• Appreciation of the roles of extracellular vesicles and the development of tools to probe their mechanism of action and function

• Advances in "omics" technologies and integration of "omic" data

• Emergence of microfluidic... more »

Voting

8 votes
Ideate

The Human Placenta Project

Standardization of tissue processing and storage in repositories, and collection and sharing of data

A recurring theme throughout the pre-meeting reports is the need to establish standards for generation of repositories of well phenotyped placental tissue samples with collection and storage in a manner that allows comparable analysis utilizing contemporary techniques across different laboratories. Additionally the need for collection of biospecimens across the entirety of normal gestation with collection of appropriate... more »

Voting

5 votes
Ideate

The Human Placenta Project

Big Data, AI/ML: Treasure Chest of Pandora's box?

Women's health and obstetrics in general, and the placenta, in particular, have not received the same level of research focus as many specific disease areas in spite of impacting much greater numbers of people because of appropriate limitation in experimental approaches. The measurement and aggregation of significant data over the course of a pregnancy (and post-partum) involving clinical and physiological biomarkers... more »

Voting

1 vote
Ideate

The Human Placenta Project

Integrated study of placenta and pregnancy, towards personalized medicine

Unlike any other pathologies, adverse pregnancy can be captured from its inception to its conclusion as these are well-defined start and endpoints. Additionally, pregnancy occurs in a defined time frame lasting less than a year (<42 weeks). Nearly all other pathologies develop over years or decades. Relative to other extensive population studies like the Framingham heart study following pregnancy from conception to delivery... more »

Voting

1 vote
Ideate