Showing 5 ideas for tag "placentalinsufficiency"

The Human Placenta Project

placental abnormalities in stillbirth and second trimester losses

During my work with the Wisconsin Stillbirth Service Program, I have found that in stillbirths and second trimester miscarriages, including those attributed to "maternal causes" such as incompetent cervix, PPROM, etc. or acute placental and cord problems such as cord "accident" or abruption, the placenta is usually small with underlying chronic abnormalities. Detailed evaluation of the placenta in stillbirth and second... more »

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The Human Placenta Project

Genetic variants and placental function

Our research group in the NIDDK Intramural Research Program has investigated the risk of APOL1 genetic variants in many types of kidney diseases, including focal segmental nephrosclerosis, HIV-associated nephropathy, and hypertension-attributed kidney disease. Together, these disease account for much of the excess chronic kidney disease risk among African-Americans.

We are accumulating evidence that APOL1 risk variants... more »

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The Human Placenta Project

Can VEGF be used as an early marker of preeclampsia?

The proper identification and clinical management of preeclampsia have been my passion since becoming an ob-gyn physician in 1987. The disproportionate deaths of pregnant women and new moms who look like me are unsettling. Early angiogenic markers that help identify increased risk factors for the diagnosis of preeclampsia would be monumental. I hope you will consider it as an area of future research, taking into consideration.... more »

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The Human Placenta Project

Is VEGF the cause of multi-organ dysfunction during preeclampsia ?

The proper identification and clinical management of preeclampsia have been my passion since becoming an ob-gyn physician in 1987. The disproportionate deaths of pregnant women and new moms, especially women of color are unsettling. Early angiogenic markers that help identify increased risk factors for the diagnosis of preeclampsia would be monumental.

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