It is well established that protein expression is different in placental cells of pregnancies that developed placental disorders including severe preeclampsia (PE). This idea exploits the fact that the placenta naturally sheds hundreds of trophoblast cells into the cervical canal... more »
The hypothesis is that a symbiotic relationship exists between the placenta and the fetal brain. A healthy placenta leads to healthy brain development in the fetus. Studies are warranted to find the correlation between the placenta and the fetal brain and the various clinical biomarkers and circulating factors aiding this process and the hypoxia-ischemia pathway
In humans, studies that consider the placenta as a mediator of the maternal environment (e.g., biomarkers, exercise) on pregnancy outcomes and in diverse populations are lacking.
• Ensure that people with disabilities (PWD) are included among the subject populations – and special efforts are made to support their reproductive health and opportunities. Often, PWD are not asked about reproductive health and are not offered... more »
Identify epigenetic signatures in the methylation of cell free DNA and correlate with placental function.